Package: ssizeRNA Type: Package Title: Sample Size Calculation for RNA-Seq Experimental Design Version: 1.3.3 Date: 2025-04-08 Authors@R: c( person("Ran", "Bi", email = "biranpier@gmail.com", role = c("aut", "cre")), person("Peng", "Liu", email = "pliu@iastate.edu", role = "aut"), person("Tim", "Triche", email = "tim.triche@gmail.com", role = "ctb")) Maintainer: Ran Bi Description: We propose a procedure for sample size calculation while controlling false discovery rate for RNA-seq experimental design. Our procedure depends on the Voom method proposed for RNA-seq data analysis by Law et al. (2014) and the sample size calculation method proposed for microarray experiments by Liu and Hwang (2007) . We develop a set of functions that calculates appropriate sample sizes for two-sample t-test for RNA-seq experiments with fixed or varied set of parameters. The outputs also contain a plot of power versus sample size, a table of power at different sample sizes, and a table of critical test values at different sample sizes. To install this package, please use 'source("http://bioconductor.org/biocLite.R"); biocLite("ssizeRNA")'. For R version 3.5 or greater, please use 'if(!requireNamespace("BiocManager", quietly = TRUE)){install.packages("BiocManager")}; BiocManager::install("ssizeRNA")'. Depends: R (>= 3.2.3) Imports: MASS, Biobase, edgeR, limma, qvalue, ssize.fdr, graphics, stats VignetteBuilder: knitr Suggests: knitr License: GPL (>= 2) biocViews: GeneExpression, DifferentialExpression, ExperimentalDesign, Sequencing, RNASeq, DNASeq, Microarray RoxygenNote: 6.1.1 NeedsCompilation: no Packaged: 2026-09-26 06:59:07 UTC; root Author: Ran Bi [aut, cre], Peng Liu [aut], Tim Triche [ctb] Config/pak/sysreqs: libicu-dev Repository: https://ranbi1990.r-universe.dev Date/Publication: 2025-04-08 23:30:03 UTC RemoteUrl: https://github.com/cran/ssizeRNA RemoteRef: HEAD RemoteSha: fab65408eee42fc2f3bee1470f25b55cf91aa522