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  "Title": "Sample Size Calculation for RNA-Seq Experimental Design",
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  "Date": "2025-04-08",
  "Authors@R": "c(\nperson(\"Ran\", \"Bi\", email = \"biranpier@gmail.com\", role = c(\"aut\", \"cre\")),\nperson(\"Peng\", \"Liu\", email = \"pliu@iastate.edu\", role = \"aut\"),\nperson(\"Tim\", \"Triche\", email = \"tim.triche@gmail.com\", role = \"ctb\"))",
  "Maintainer": "Ran Bi <biranpier@gmail.com>",
  "Description": "We propose a procedure for sample size calculation while\ncontrolling false discovery rate for RNA-seq experimental\ndesign. Our procedure depends on the Voom method proposed for\nRNA-seq data analysis by Law et al. (2014)\n<DOI:10.1186/gb-2014-15-2-r29> and the sample size calculation\nmethod proposed for microarray experiments by Liu and Hwang\n(2007) <DOI:10.1093/bioinformatics/btl664>. We develop a set of\nfunctions that calculates appropriate sample sizes for\ntwo-sample t-test for RNA-seq experiments with fixed or varied\nset of parameters. The outputs also contain a plot of power\nversus sample size, a table of power at different sample sizes,\nand a table of critical test values at different sample sizes.\nTo install this package, please use\n'source(\"http://bioconductor.org/biocLite.R\");\nbiocLite(\"ssizeRNA\")'. For R version 3.5 or greater, please use\n'if(!requireNamespace(\"BiocManager\", quietly =\nTRUE)){install.packages(\"BiocManager\")};\nBiocManager::install(\"ssizeRNA\")'.",
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  "License": "GPL (>= 2)",
  "biocViews": "GeneExpression, DifferentialExpression, ExperimentalDesign,\nSequencing, RNASeq, DNASeq, Microarray",
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  "Author": "Ran Bi [aut, cre], Peng Liu [aut], Tim Triche [ctb]",
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